What is Lewy body dementia?
LBD is caused by alpha-synuclein protein deposits — third most common dementia. Core features: fluctuating cognition, visual hallucinations, parkinsonism, REM sleep behavior disorder.
Related: Cognitive Care → · Dr. Jitendra Knowledge Hub → · ICHD-3 Topic →
Diagnosis
Clinical criteria: dementia + 2 of 3 core features, or 1 core + biomarker. MRI often normal early. DaTscan may help.
Treatment
Cholinesterase inhibitors, memantine, careful dopaminergic treatment for parkinsonism. Avoid antipsychotics (severe sensitivity). Caregiver support essential.