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Air pollution (PM2.5) affects brain health — linked to stroke, cognitive decline and headache. Kathmandu has severe pollution.
Quick Answer
Air pollution (PM2.5) affects brain health — linked to stroke, cognitive decline and headache. Kathmandu has severe pollution. Dr. Jitendra Prasad Yadav (NMC 8029, 15+ years of clinical experience) evaluates air pollution neurological effects at Kathmandu Neurology Clinic & Cognitive Center, 117 Lal Durbar Marg, Kathmandu, Bagmati Province 44600, Nepal — evidence-based, medically reviewed.
Fine particulate matter (PM2.5) penetrates deep into lungs, enters bloodstream and crosses the blood-brain barrier — triggering inflammation, oxidative stress and vascular damage in the brain. Chronic exposure is associated with accelerated cognitive decline, increased stroke risk, and higher dementia rates. Kathmandu Valley has some of the world's highest PM2.5 levels.
Irritability
Respiratory symptoms (cough, wheezing)
Management is individualized and discussed with benefits, limitations, and follow-up.
Eye irritation
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Reviewed by Dr. Jitendra Prasad Yadav • Last reviewed: 2026-11-10
Content is educational and aligns with standard medical references; individual evaluation may vary. External links provide context and do not imply endorsement.
Doctor — medically reviewed
Dr. Jitendra Prasad Yadav
Consultant Neurologist & Headache Specialist • MBBS, MD (Internal Medicine), FICN (Neurology), FCNV, FIHM • NMC 8029
This condition guide was medically reviewed by Dr. Jitendra Prasad Yadav.
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Emergency
For sudden neurologic change, thunderclap headache, or seizure >5 min, seek emergency services now.